Patient Profile
- Sex / Age:
- Female, 45 years
- Height / Weight:
- 166 cm / 88 kg (BMI 31.9)
- Reported symptoms:
- Recurrent right upper quadrant pain after fatty meals, lasting 1–3 hours; episode tonight ongoing 4 h, with one episode of vomiting; mild fever (37.6 °C)
- Examination:
- RUQ tenderness, positive Murphy's sign reported clinically; no jaundice
- History:
- Two pregnancies, oral contraceptive use, family history of cholelithiasis (mother)
Summary Overview
Right upper quadrant ultrasound demonstrates cholelithiasis with sonographic features of acute cholecystitis: gallbladder wall thickening, pericholecystic fluid, and a sonographic Murphy's sign. No biliary ductal dilation. Liver, pancreas (visualized portions), and kidneys appear unremarkable.
Detailed Imaging Findings
Differential Diagnosis
-
Acute calculous cholecystitisHigh
Stones + wall thickening + pericholecystic fluid + sonographic Murphy's = classic combination [Pinto A 2013; Tokyo Guidelines TG18, J Hepatobiliary Pancreat Sci 2018].
-
Symptomatic cholelithiasis (biliary colic) without inflammationLow
Less likely given inflammatory features. Distinguishing requires correlation with WBC, fever, and clinical course.
-
Choledocholithiasis / cholangitisLow
CBD not dilated and no jaundice; correlation with LFTs and lipase recommended. MRCP/EUS if biochemical suspicion arises.
-
Gallbladder polyp / massLow
No fixed mural lesion identified. The visualized echogenic foci shadow and move with positioning, consistent with stones rather than polyps.
Analytical Summary & Recommendations
Imaging impression
Findings are highly suggestive of acute calculous cholecystitis. Imaging by itself does not establish severity grade; clinical and laboratory data are needed.
Recommended next steps (clinical correlation)
- Correlate with WBC, CRP, LFTs (AST, ALT, ALP, total bilirubin), and lipase
- Apply Tokyo Guidelines (TG18) criteria for diagnosis and severity grading [Yokoe M, J Hepatobiliary Pancreat Sci 2018]
- Surgical consultation for laparoscopic cholecystectomy within 72 hours of symptom onset (preferred for early cholecystitis) [Gurusamy KS, Cochrane 2013]
- If poor surgical candidate: IV antibiotics, supportive care, and percutaneous cholecystostomy as bridge therapy
- If LFTs become abnormal or duct dilation develops: MRCP / EUS to evaluate for CBD stones
Key Questions for Your Physician
- Do I need surgery now, or can this be managed first with antibiotics and surgery later?
- What blood tests do you want to check before deciding?
- Are there signs of complications (perforation, gangrene, bile duct involvement)?
- What dietary and lifestyle changes should I make if surgery is delayed?
- What red-flag symptoms should send me back to the emergency department immediately?
What This Means for You
Your ultrasound shows gallstones and signs that your gallbladder is inflamed — a condition called acute cholecystitis. The pain you have been having after fatty meals, combined with the current longer-lasting episode, fits well with this diagnosis.
The standard treatment is removal of the gallbladder (cholecystectomy), usually performed laparoscopically within a few days of presentation. This is one of the most common operations and recovery is typically fast. In some situations (very high surgical risk, poor general condition), the team may choose to control the inflammation first with antibiotics or a temporary drain, and operate later.
Your bile duct looks normal and there is no jaundice, which is reassuring — there is no current evidence that a stone has moved into the duct. Your liver and kidneys also look normal.
Go to emergency care immediately if your pain becomes severe and unrelenting, you develop high fever, your skin or eyes turn yellow, or you feel dizzy/lightheaded.
High confidence in cholecystitis given multi-parameter sonographic concordance and characteristic clinical features. Final severity grading and surgical timing are clinical decisions.
References
- Yokoe M, Hata J, Takada T, et al. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis. J Hepatobiliary Pancreat Sci 2018;25(1):41–54.
- Pinto A, Reginelli A, Cagini L, et al. Accuracy of ultrasonography in the diagnosis of acute calculous cholecystitis: review of the literature. Crit Ultrasound J 2013;5(Suppl 1):S11.
- Gurusamy KS, Davidson C, Gluud C, Davidson BR. Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis. Cochrane Database Syst Rev 2013;(6):CD005440.
- ACR Appropriateness Criteria — Right Upper Quadrant Pain. American College of Radiology 2018.
- Strasberg SM. Clinical practice. Acute calculous cholecystitis. NEJM 2008;358(26):2804–11.